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Journal article

Genetic contribution to radiographic severity in osteoarthritis of the knee.

Abstract:

OBJECTIVE: Knee osteoarthritis (OA) has a significant genetic component. The authors have assessed the role of three variants reported to influence risk of knee OA with p<5×10-8 in determining patellofemoral and tibiofemoral Kellgren Lawrence (K/L) grade in knee OA cases. METHODS: 3474 knee OA cases with sky-line and weight-bearing antero-posterior x-rays of the knee were selected based on the presentation of K/L grade ≥2 at either the tibiofemoral or patellofemoral compartments for one or...

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Publication status:
Published

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Authors


Valdes, AM More by this author
Doherty, S More by this author
Maciewicz, RA More by this author
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Journal:
Annals of the rheumatic diseases
Volume:
71
Issue:
9
Pages:
1537-1540
Publication date:
2012-09-05
DOI:
EISSN:
1468-2060
ISSN:
0003-4967
URN:
uuid:345edf55-0035-46ea-b86c-f7721289b669
Source identifiers:
334637
Local pid:
pubs:334637

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