Low plasma iron status and akathisia.

Journal article

Thirty patients were examined to test the hypothesis that a depletion of iron levels is associated with symptoms of akathisia. Fifteen akathisic patients were pair-matched with 15 non-akathisic patients. Plasma ferritin levels were significantly decreased in the akathisic patients, and there was a significant inverse correlation between plasma iron levels and akathisia rating. In addition, akathisia ratings were found to be correlated with a scale measuring symptoms of tardive dyskinesia.

Authors: Barton, A; Bowie, J; Ebmeier, K

• Journal: Journal of neurology, neurosurgery, and psychiatry
• Volume: 53
• Issue: 8
• Pages: 671-674
• Publication date: 1990-08-01
• DOI: 10.1136/jnnp.53.8.671
• EISSN: 1468-330X
• ISSN: 0022-3050
• Language: English
• Keywords: Female; Humans; Antipsychotic Agents; Psychomotor Agitation; Dose-Response Relationship, Drug; Akathisia, Drug-Induced; Risk Factors; Iron; Middle Aged; Adult; Male; Dyskinesia, Drug-Induced; Anemia, Hypochromic; Transferrin-Binding Proteins; Iron-Binding Proteins; Ferritins; Carrier Proteins