Age-Related Differences and Heritability of the Perisylvian Language Networks

Journal article

The field of neuroanatomy of language is moving forward at a fast pace. This progression is partially due to the development of diffusion tractography, which has been used to describe white matter connections in the living human brain. For the field of neurolinguistics this advancement is timely and important for two reasons. First, it allows clinical researchers to liberate themselves from neuroanatomical models of language derived from animal studies. Second, for the first time, it offers the possibility of testing network correlates of neurolinguistic models directly in the human brain. This chapter introduces the reader to general principles of diffusion imaging and tractography. Examples of its applications, such as tract analysis, will be used to explicate its potentials and limitations

Authors: Budisavljevic, S; Dell'Acqua, F; Rijsdijk, FV; Kane, F; Picchioni, M

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Society for Neuroscience
• Journal: The Journal of Neuroscience
• Volume: 35
• Issue: 37
• Pages: 12625-12634
• Publication date: 2015-09-16
• DOI: 10.1523/jneurosci.1255-14.2015
• EISSN: 1529-2401
• ISSN: 0270-6474
• Language: English
• Keywords: Population; Medicine; Neuroscience; Audiology; Magnetic resonance imaging; Heritability; Evolutionary biology; Tractography; Anatomy; Arcuate fasciculus; Lateralization of brain function; Psychology; Diffusion MRI; Developmental psychology; Biology