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Paramedic analgesia comparing ketamine and morphine in trauma (PACKMaN): a randomised, double-blind, phase 3 trial

Abstract:
Background
Paramedics frequently administer analgesic medications for pain following trauma. Morphine is the most commonly administered strong analgesic. However, it may not be the best option as it may lower blood pressure, depress respiration and there is a risk of dependency. Ketamine might be a better option due to speed of onset and favourable side-effect profile. We sought to compare clinical effectiveness of paramedic administered ketamine and morphine in patients w... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.lanepe.2025.101265

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Role:
Author
ORCID:
0000-0003-0220-2223


Publisher:
Elsevier
Journal:
Lancet Regional Health - Europe More from this journal
Volume:
53
Article number:
101265
Publication date:
2025-04-05
Acceptance date:
2025-02-28
DOI:
EISSN:
2666-7762


Language:
English
Keywords:
Pubs id:
2108638
Local pid:
pubs:2108638
Deposit date:
2025-04-08
ARK identifier:

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