Journal article
Role of ciliary protein intraflagellar transport protein 88 in the regulation of cartilage thickness and osteoarthritis development in mice
- Abstract:
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Objective
Mechanical and biologic cues drive cellular signaling in cartilage development, health, and disease. Primary cilia proteins, which are implicated in the transduction of biologic and physiochemical signals, control cartilage formation during skeletal development. This study was undertaken to assess the influence of the ciliary protein intraflagellar transport protein 88 (IFT88) on postnatal cartilage from mice with conditional knockout of the Ift88 gene (Ift... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 21.1MB, Terms of use)
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- Publisher copy:
- 10.1002/art.41894
Authors
- Publisher:
- Wiley
- Journal:
- Arthritis and Rheumatology More from this journal
- Volume:
- 74
- Issue:
- 1
- Pages:
- 49-59
- Publication date:
- 2021-12-16
- Acceptance date:
- 2021-06-03
- DOI:
- EISSN:
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2326-5205
- ISSN:
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2326-5191
- Language:
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English
- Keywords:
- Pubs id:
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1123706
- Local pid:
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pubs:1123706
- Deposit date:
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2021-06-10
- ARK identifier:
Terms of use
- Copyright holder:
- Coveney et al.
- Copyright date:
- 2021
- Rights statement:
- © 2021 The Authors. Arthritis & Rheumatology published by Wiley Periodicals LLC on behalf of American College of Rheumatology. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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