Journal article icon

Journal article

Subthalamic nucleotomy alleviates parkinsonism in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-exposed primate.

Abstract:
Research into the neural mechanisms underlying the symptoms of parkinsonism utilizing the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-exposed primate model have shown that the subthalamic nucleus (STN) occupies a central role. As a logical development of this theory, we have studied the effects of thermocoagulative lesions of the STN in the primate model. Such lesions can cause remarkable symptom reversal in the experimental primate model.
Publication status:
Published

Actions


Access Document


Publisher copy:
10.3109/02688699209002375

Authors


Journal:
British journal of neurosurgery
Volume:
6
Issue:
6
Pages:
575-582
Publication date:
1992-01-01
DOI:
EISSN:
1360-046X
ISSN:
0268-8697
Source identifiers:
252497
Language:
English
Keywords:
Pubs id:
pubs:252497
UUID:
uuid:32d93a25-605e-4ae7-b78b-9b13505e6f35
Local pid:
pubs:252497
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP