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The design of microfluidic affinity chromatography systems for the separation of bioanalytes.

Abstract:

The analytical (numerical) design of planar microfluidic affinity chromatography devices, which consist of multiple separation lanes and multiple, different surface-immobilised receptor patterns in each lane, is described. The model is based on the analytical solution of the transport-reaction equations in microfluidic systems of low Gratz number and for injection of small analyte plugs. The results reveal a simple approach for the design of microfluidic affinity chromatography devices tailor...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
Role:
Author
Journal:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Volume:
910
Pages:
163-171
Publication date:
2012-12-05
DOI:
EISSN:
1873-376X
ISSN:
1570-0232
URN:
uuid:32d2061e-5cf8-4ff5-aed4-78cb5d935991
Source identifiers:
357196
Local pid:
pubs:357196

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