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Estimating divergence time and ancestral effective population size of Bornean and Sumatran orangutan subspecies using a coalescent hidden Markov model.

Abstract:

Due to genetic variation in the ancestor of two populations or two species, the divergence time for DNA sequences from two populations is variable along the genome. Within genomic segments all bases will share the same divergence-because they share a most recent common ancestor-when no recombination event has occurred to split them apart. The size of these segments of constant divergence depends on the recombination rate, but also on the speciation time, the effective population size of the a...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pgen.1001319

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
European Research Area in Plant Genomics ARelatives More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS genetics Journal website
Volume:
7
Issue:
3
Article number:
e1001319
Publication date:
2011-03-01
DOI:
EISSN:
1553-7404
ISSN:
1553-7390
Source identifiers:
124374

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