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Thesis

Investigating the neurochemical basis of action initiation, selection, and inhibition

Abstract:

Two central monoamine systems, dopamine and serotonin, are thought to be integral to the promotion or inhibition of goal-directed action respectively, but how this information is conveyed in tandem with reward-related signals is not yet fully understood. In particular, whilst reward prediction error encoding by midbrain dopamine activity and release is well replicated, this contrasts with a wealth of pharmacological evidence emphasising dopamine’s role in activation of behaviour for reward...

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Department:
University of Oxford
Role:
Supervisor
Department:
University of Oxford
Role:
Supervisor
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Grant:
ES/J500112/1
Funding agency for:
Laura Lucy Grima
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Funding agency for:
Laura Lucy Grima
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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