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Direct access to optical aberration information in fluorescence laser scanning microscopy using detector arrays

Abstract:

In the recent years, numerous adaptive optics techniques have emerged to address optical aberrations in fluorescence microscopy imaging. However, many existing methods involve complex hardware implementations or lengthy iterative algorithms that may induce photo-damage to the sample. Our study proposes an innovative approach centered around a novel detector array capable of potentially capturing the probed sample in a single acquisition. Our solution is gentle on the sample and applicable to ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1117/12.3000914

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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
ORCID:
0000-0002-9525-8981
Publisher:
Society of Photo-optical Instrumentation Engineers
Host title:
Progress in Biomedical Optics and Imaging
Volume:
12851
Article number:
1285102
Publication date:
2024-03-12
Acceptance date:
2024-03-12
Event title:
Adaptive Optics and Wavefront Control for Biological Systems X
DOI:
ISSN:
1605-7422
ISBN:
9781510669611
Language:
English
Keywords:
Pubs id:
1988375
Local pid:
pubs:1988375
Deposit date:
2024-05-12

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