Journal article icon

Journal article

Inducible expression of the cell surface heparan sulfate proteoglycan syndecan-2 (fibroglycan) on human activated macrophages can regulate fibroblast growth factor action.

Abstract:

Monocyte/macrophages play important roles in regulating tissue growth and angiogenesis through the controlled release of heparin-binding growth factors such as fibroblast growth factor (FGF), vascular endothelial growth factor, and heparin binding epidermal growth factor. The action of these potent growth mediators is known to be regulated by adsorption to heparan sulfate proteoglycans (HSPGs) on the surface and within the extracellular matrix of other neighboring cells, which respectively pr...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1074/jbc.274.34.24113

Authors


Clasper, S More by this author
Vekemans, S More by this author
Plebanski, M More by this author
Wordsworth, P More by this author
Expand authors...
Journal:
The Journal of biological chemistry
Volume:
274
Issue:
34
Pages:
24113-24123
Publication date:
1999-08-05
DOI:
EISSN:
1083-351X
ISSN:
0021-9258
URN:
uuid:3266252b-10e7-46c8-8d4f-36fbf51176e7
Source identifiers:
102541
Local pid:
pubs:102541

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP