Journal article
Global and regional burden of chronic respiratory disease in 2016 arising from non-infectious airborne occupational exposures: a systematic analysis for the Global Burden of Disease Study 2016
- Abstract:
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Objectives This paper presents detailed analysis of the global and regional burden of chronic respiratory disease arising from occupational airborne exposures, as estimated in the Global Burden of Disease 2016 study.
Methods The burden of chronic obstructive pulmonary disease (COPD) due to occupational exposure to particulate matter, gases and fumes, and secondhand smoke, and the burden of asthma resulting from occupational exposure to asthmagens, was estimated using the population attributable fraction (PAF), calculated using exposure prevalence and relative risks from the literature. PAFs were applied to the number of deaths and disability-adjusted life years (DALYs) for COPD and asthma. Pneumoconioses were estimated directly from cause of death data. Age-standardised rates were based only on persons aged 15 years and above.
Results The estimated PAFs (based on DALYs) were 17% (95% uncertainty interval (UI) 14%–20%) for COPD and 10% (95% UI 9%–11%) for asthma. There were estimated to be 519 000 (95% UI 441,000–609,000) deaths from chronic respiratory disease in 2016 due to occupational airborne risk factors (COPD: 460,100 [95% UI 382,000–551,000]; asthma: 37,600 [95% UI 28,400–47,900]; pneumoconioses: 21,500 [95% UI 17,900–25,400]. The equivalent overall burden estimate was 13.6 million (95% UI 11.9–15.5 million); DALYs (COPD: 10.7 [95% UI 9.0–12.5] million; asthma: 2.3 [95% UI 1.9–2.9] million; pneumoconioses: 0.58 [95% UI 0.46–0.67] million). Rates were highest in males; older persons and mainly in Oceania, Asia and sub-Saharan Africa; and decreased from 1990 to 2016.
Conclusions Workplace exposures resulting in COPD, asthma and pneumoconiosis continue to be important contributors to the burden of disease in all regions of the world. This should be reducible through improved prevention and control of relevant exposures.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, 272.0KB, Terms of use)
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- Publisher copy:
- 10.1136/oemed-2019-106013
Authors
Contributors
+ GBD 2016 Occupational Chronic Respiratory Risk Factors Collaborators
- Role:
- Contributor
- Publisher:
- BMJ Publishing Group
- Journal:
- Occupational and Environmental Medicine More from this journal
- Volume:
- 77
- Issue:
- 3
- Pages:
- 142-150
- Publication date:
- 2020-03-13
- Acceptance date:
- 2019-11-30
- DOI:
- EISSN:
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1470-7926
- ISSN:
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1351-0711
- Pmid:
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32054818
- Language:
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English
- Keywords:
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- Pubs id:
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1204435
- Local pid:
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pubs:1204435
- Deposit date:
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2021-10-21
Terms of use
- Copyright holder:
- GBD 2016 Occupational Chronic Respiratory Risk Factors Collaborators
- Copyright date:
- 2020
- Rights statement:
- ©2020 Author(s) (or their employer(s)). Re-use permitted under CC BY. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
- Licence:
- CC Attribution (CC BY)
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