Journal article
Paradoxical reaction to antitubercular treatment in a case of pulmonary tuberculosis
- Abstract:
- A 51-year-old man presented with intermittent fever, mild cough and loss of appetite of 1-month duration. His sputum smear was positive for acid-fast bacilli and his chest radiograph revealed apical infiltrations. The patient was treated with antitubercular therapy (ATT), recovered and was well for 1 month, after which he suddenly developed focal seizures. MRI of the brain with gadolinium enhancement showed high intensity nodular foci in the frontal, parietal and occipital regions. The patient was diagnosed as a case of paradoxical reaction to ATT, and was successfully managed with continued ATT and adjunctive steroid therapy.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Accepted manuscript, pdf, 48.3KB, Terms of use)
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(Preview, Figures/images, pdf, 397.2KB, Terms of use)
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- Publisher copy:
- 10.1136/bcr-2015-214285
Authors
- Publisher:
- BMJ Publishing Group
- Journal:
- BMJ Case Reports More from this journal
- Volume:
- 2016
- Article number:
- bcr2015214285
- Publication date:
- 2016-02-17
- Acceptance date:
- 2016-02-04
- DOI:
- EISSN:
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1757-790X
- Language:
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English
- Pubs id:
-
pubs:606225
- UUID:
-
uuid:322e0b14-97fb-441d-abae-2934f542dc52
- Local pid:
-
pubs:606225
- Source identifiers:
-
606225
- Deposit date:
-
2016-02-25
Terms of use
- Copyright holder:
- BMJ Publishing Group
- Copyright date:
- 2016
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from BMJ Publishing Group at https://dx.doi.org/10.1136/bcr-2015-214285
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