Journal article

Targeting MAIT cells as a cellular adjuvant for humoral immunity: a new player in a very old game

Abstract:: In this article, I discuss recent work by Pankhurst et al. They found that MAIT cells can serve as a cellular adjuvant to boost immunity to a protein adjuvant. Intranasal co-administration of protein antigen with a strong MAIT cell ligand results in the the production of mucosal IgA and IgG antibody responses. This process is driven by MAIT cell-mediated maturation of migratory dendritic cells.

Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Provine, N. M. (2023). Targeting MAIT cells as a cellular adjuvant for humoral immunity: a new player in a very old game. Immunology and Cell Biology, 101(6), 470–472.

MLA Style

Provine, N. M. “Targeting MAIT Cells as a Cellular Adjuvant for Humoral Immunity: a New Player in a Very Old Game.” Immunology and Cell Biology, vol. 101, no. 6, Wiley, 2023, pp. 470–72.

Chicago Style

Provine, NM. 2023. “Targeting MAIT Cells as a Cellular Adjuvant for Humoral Immunity: a New Player in a Very Old Game.” Immunology and Cell Biology 101 (6): 470–72.
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Files:: Provine_2023_Targeting_MAIT_cells.pdf

(Preview, Accepted manuscript, pdf, 952.3KB, Terms of use)

Publisher copy:: 10.1111/imcb.12648

Authors

+ Provine, NM More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Tropical Medicine
Role:: Author

Publisher:: Wiley
Journal:: Immunology and Cell Biology More from this journal
Volume:: 101
Issue:: 6
Pages:: 470-472
Place of publication:: United States
Publication date:: 2023-05-03
Acceptance date:: 2023-04-09
DOI:: 10.1111/imcb.12648
EISSN:: 1440-1711
ISSN:: 0818-9641
Pmid:: 37137689

Language:: English
Keywords:: antibody formation

adjuvants

mucosal

cellular

intranasal

administration

mucosal-associated invariant t cells

immunity

immunologic

humoral
Pubs id:: 1341071
Local pid:: pubs:1341071
Deposit date:: 2024-02-08

Terms of use

Copyright holder:: Australian and New Zealand Society for Immunology, Inc.
Copyright date:: 2023
Rights statement:: © 2023 the Australian and New Zealand Society for Immunology, Inc.
Notes:: This is the accepted manuscript version of the article. The final version is available online from Wiley at https://dx.doi.org/10.1111/imcb.12648

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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