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Mapping of the fibroblast growth factors in human white adipose tissue.

Abstract:

CONTEXT: Fibroblast growth factors (FGFs) regulate the development of white adipose tissue (WAT). However, the secretion and cellular origin of individual FGFs in WAT as well as the influence of obesity are unknown. OBJECTIVE: Our objective was to map FGFs in human sc WAT, the cellular source, and association with obesity. DESIGN: Secretion, mRNA, and circulatory levels of FGFs in human abdominal sc WAT from nonobese and obese donors were examined by microarray, real-time quantitative PCR, a...

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Publication status:
Published

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Publisher copy:
10.1210/jc.2009-2049

Authors


Mejhert, N More by this author
Galitzky, J More by this author
Pettersson, AT More by this author
Bambace, C More by this author
Blomqvist, L More by this author
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Journal:
The Journal of clinical endocrinology and metabolism
Volume:
95
Issue:
5
Pages:
2451-2457
Publication date:
2010-05-05
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
URN:
uuid:3138d036-fdf4-4217-aa2a-4c466ec3cc1a
Source identifiers:
51907
Local pid:
pubs:51907

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