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Efficacy of tofacitinib for the treatment of psoriatic arthritis: pooled analysis of two phase 3 studies

Abstract:
Introduction Tofacitinib is an oral Janus kinase inhibitor for the treatment of psoriatic arthritis (PsA). This post hoc analysis assessed the efficacy of tofacitinib using pooled data from two phase 3 studies of patients with active PsA.

Methods Data were pooled from OPAL Broaden (NCT01877668) and OPAL Beyond (NCT01882439). Patients had active PsA and either an inadequate response (IR) to ≥ 1 conventional synthetic disease-modifying antirheumatic ... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1007/s40744-018-0131-5

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Subgroup:
Botnar Research Centre
ORCID:
0000-0002-4756-663X
Fleischmann, R More by this author
Gomez-Reino, JJ More by this author
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Publisher:
Springer Nature Publisher's website
Journal:
Rheumatology and Therapy Journal website
Volume:
5
Issue:
2
Pages:
567–582
Publication date:
2018-11-09
Acceptance date:
2018-10-15
DOI:
EISSN:
2198-6584
ISSN:
2198-6576
Pubs id:
pubs:945736
URN:
uri:30f608e0-1186-41ab-b8cf-a25d68c0f82e
UUID:
uuid:30f608e0-1186-41ab-b8cf-a25d68c0f82e
Local pid:
pubs:945736

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