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Robust Gag-specific T cell responses characterize viremia control in HIV-2 infection.

Abstract:

HIV-2 infection in the majority of infected subjects follows an attenuated disease course that distinguishes it from infection with HIV-1. Antigen-specific T cells are pivotal in the management of chronic viral infections but are not sufficient to control viral replication in HIV-1-positive subjects, and their function in HIV-2 infection is not fully established. In a community-based cohort of HIV-2 long-term nonprogressors in rural Guinea-Bissau, we performed what we believe is the first com...

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Publisher copy:
10.1172/jci32380

Authors


Leligdowicz, A More by this author
Yindom, LM More by this author
Onyango, C More by this author
Sarge-Njie, R More by this author
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Journal:
The Journal of clinical investigation
Volume:
117
Issue:
10
Pages:
3067-3074
Publication date:
2007-10-05
DOI:
EISSN:
1558-8238
ISSN:
0021-9738
URN:
uuid:30df3c0e-3a6c-462d-999f-ae91f4c99bbb
Source identifiers:
95889
Local pid:
pubs:95889

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