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Journal article

Phenotypic analysis of antigen-specific T lymphocytes.

Abstract:

Identification and characterization of antigen-specific T lymphocytes during the course of an immune response is tedious and indirect. To address this problem, the peptide-major histocompatability complex (MHC) ligand for a given population of T cells was multimerized to make soluble peptide-MHC tetramers. Tetramers of human lymphocyte antigen A2 that were complexed with two different human immunodeficiency virus (HIV)-derived peptides or with a peptide derived from influenza A matrix protein...

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Publication status:
Published

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Publisher copy:
10.1126/science.274.5284.94

Authors


Altman, JD More by this author
Goulder, PJ More by this author
Barouch, DH More by this author
McHeyzer-Williams, MG More by this author
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Journal:
Science (New York, N.Y.)
Volume:
274
Issue:
5284
Pages:
94-96
Publication date:
1996-10-05
DOI:
EISSN:
1095-9203
ISSN:
0036-8075
URN:
uuid:30da732b-b95c-43e6-a952-e8bb7f445aeb
Source identifiers:
45290
Local pid:
pubs:45290

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