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A new statistical method for haplotype reconstruction from population data.

Abstract:

Current routine genotyping methods typically do not provide haplotype information, which is essential for many analyses of fine-scale molecular-genetics data. Haplotypes can be obtained, at considerable cost, experimentally or (partially) through genotyping of additional family members. Alternatively, a statistical method can be used to infer phase and to reconstruct haplotypes. We present a new statistical method, applicable to genotype data at linked loci from a population sample, that impr...

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Publication status:
Published

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Publisher copy:
10.1086/319501

Authors


Stephens, M More by this author
Donnelly, P More by this author
Journal:
American journal of human genetics
Volume:
68
Issue:
4
Pages:
978-989
Publication date:
2001-04-05
DOI:
EISSN:
1537-6605
ISSN:
0002-9297
URN:
uuid:303b6388-a5ce-44b7-b057-18854cd1fffb
Source identifiers:
49969
Local pid:
pubs:49969

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