Pfam is a widely used database of protein families and domains. This article describes a set of major updates that we have implemented in the latest release (version 24.0). The most important change is that we now use HMMER3, the latest version of the popular profile hidden Markov model package. This software is approximately 100 times faster than HMMER2 and is more sensitive due to the routine use of the forward algorithm. The move to HMMER3 has necessitated numerous changes to Pfam that are...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
The Pfam protein families database.
If you are the owner of this record, you can report an update to it here: Report update to this record