- Abstract:
-
Human immunodeficiency virus type-1 (HIV-1) cytotoxic T lymphocyte (CTL) epitopes have largely been defined in Caucasian populations infected with clade B virus. Identification of potentially protective CTL epitopes in non-B clade-infected African subjects is important for vaccine development. In a study of CTL responses in clade A-infected Gambians, using cytotoxicity, interferon-gamma (IFN-gamma) enzyme-linked immunospot (ELISpot) and HLA-B53-peptide tetramer assays, we identified three HLA...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/1521-4141(200106)31:6<1747::aid-immu1747>3.3.co;2-c
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- Journal:
- European journal of immunology
- Volume:
- 31
- Issue:
- 6
- Pages:
- 1747-1756
- Publication date:
- 2001-06-05
- DOI:
- EISSN:
-
1521-4141
- ISSN:
-
0014-2980
- URN:
-
uuid:2ff1c595-2833-46db-bd8e-c1a11f0a7808
- Source identifiers:
-
13931
- Local pid:
- pubs:13931
- Language:
- English
- Keywords:
- Copyright date:
- 2001
Journal article
Cytotoxic T lymphocytes recognize structurally diverse, clade-specific and cross-reactive peptides in human immunodeficiency virus type-1 gag through HLA-B53.
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