Journal article icon

Journal article

Cytotoxic T lymphocytes recognize structurally diverse, clade-specific and cross-reactive peptides in human immunodeficiency virus type-1 gag through HLA-B53.

Abstract:

Human immunodeficiency virus type-1 (HIV-1) cytotoxic T lymphocyte (CTL) epitopes have largely been defined in Caucasian populations infected with clade B virus. Identification of potentially protective CTL epitopes in non-B clade-infected African subjects is important for vaccine development. In a study of CTL responses in clade A-infected Gambians, using cytotoxicity, interferon-gamma (IFN-gamma) enzyme-linked immunospot (ELISpot) and HLA-B53-peptide tetramer assays, we identified three HLA...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Structural Biology
Role:
Author
Expand authors...
Journal:
European journal of immunology
Volume:
31
Issue:
6
Pages:
1747-1756
Publication date:
2001-06-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:2ff1c595-2833-46db-bd8e-c1a11f0a7808
Source identifiers:
13931
Local pid:
pubs:13931

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP