Journal article icon

Journal article

The effects of selection on linkage analysis for quantitative traits.

Abstract:

The effects of within-sample selection on the outcome of analyses detecting linkage between genetic markers and quantitative traits were studied. It was found that selection by truncation for the trait of interest significantly reduces the differences between marker genotype means thus reducing the power to detect linked quantitative trait loci (QTL). The size of this reduction is a function of proportion selected, the magnitude of the QTL effect, recombination rate between the marker locus a...

Expand abstract
Publication status:
Published

Actions


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
Journal:
Genetics
Volume:
132
Issue:
4
Pages:
1177-1185
Publication date:
1992-12-05
EISSN:
1943-2631
ISSN:
0016-6731
URN:
uuid:2fe96cbf-93e1-497e-be33-995c0427d69b
Source identifiers:
90481
Local pid:
pubs:90481

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP