The effects of selection on linkage analysis for quantitative traits.

Journal article

Abstract:: The effects of within-sample selection on the outcome of analyses detecting linkage between genetic markers and quantitative traits were studied. It was found that selection by truncation for the trait of interest significantly reduces the differences between marker genotype means thus reducing the power to detect linked quantitative trait loci (QTL). The size of this reduction is a function of proportion selected, the magnitude of the QTL effect, recombination rate between the marker locus a...
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Institution:

University of Oxford

Division:

MSD

Department:

NDM

Sub department:

Tropical Medicine

Role:

Author

Role:

Author

Language:: English
Keywords:: Genetics, Population

Genotype

Animals

Breeding

Genetic Linkage

Selection, Genetic

Cattle

Gene Frequency

Models, Biological

Phenotype
Pubs id:: pubs:90481
UUID:: uuid:2fe96cbf-93e1-497e-be33-995c0427d69b
Local pid:: pubs:90481
Deposit date:: 2012-12-19

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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