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Inferring malaria parasite population structure from serological networks.

Abstract:

The malaria parasite Plasmodium falciparum is characterized by high levels of genetic diversity at antigenic loci involved in virulence and immune evasion. Knowledge of the population structure and dynamics of these genes is important for designing control programmes and understanding the acquisition of immunity to malaria; however, high rates of homologous and non-homologous recombination as well as complex patterns of expression within hosts have hindered attempts to elucidate these structu...

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Publication status:
Published

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Publisher copy:
10.1098/rspb.2008.1122

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Role:
Author
Journal:
Proceedings. Biological sciences / The Royal Society
Volume:
276
Issue:
1656
Pages:
477-485
Publication date:
2009-02-05
DOI:
EISSN:
1471-2954
ISSN:
0962-8452
URN:
uuid:2f9aa7c7-5c76-4a89-8893-1cdf5218ad2d
Source identifiers:
34407
Local pid:
pubs:34407

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