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Inferring malaria parasite population structure from serological networks.

Abstract:

The malaria parasite Plasmodium falciparum is characterized by high levels of genetic diversity at antigenic loci involved in virulence and immune evasion. Knowledge of the population structure and dynamics of these genes is important for designing control programmes and understanding the acquisition of immunity to malaria; however, high rates of homologous and non-homologous recombination as well as complex patterns of expression within hosts have hindered attempts to elucidate these structu...

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Publication status:
Published

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Publisher copy:
10.1098/rspb.2008.1122

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
Journal:
Proceedings. Biological sciences / The Royal Society
Volume:
276
Issue:
1656
Pages:
477-485
Publication date:
2009-02-01
DOI:
EISSN:
1471-2954
ISSN:
0962-8452
Source identifiers:
34407
Language:
English
Keywords:
Pubs id:
pubs:34407
UUID:
uuid:2f9aa7c7-5c76-4a89-8893-1cdf5218ad2d
Local pid:
pubs:34407
Deposit date:
2012-12-19

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