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Molecular confirmation of co-infection by pathogenic Leptospira spp. and Orientia tsutsugamushi in patients with acute febrile illness in Thailand.

Abstract:

Leptospirosis and scrub typhus are major causes of acute febrile illness in rural Asia, where co-infection is reported to occur based on serologic evidence. We re-examined whether co-infection occurs by using a molecular approach. A duplex real-time polymerase chain reaction was developed that targeted a specific 16S ribosomal RNA gene of pathogenic Leptospira spp. and Orientia tsutsugamushi. Of 82 patients with an acute febrile illness who had dual infection on the basis of serologic tests, ...

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Publication status:
Published

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Publisher copy:
10.4269/ajtmh.13-0402

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
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Journal:
American journal of tropical medicine and hygiene
Volume:
89
Issue:
4
Pages:
797-799
Publication date:
2013-10-01
DOI:
EISSN:
1476-1645
ISSN:
0002-9637
Source identifiers:
421056
Language:
English
Keywords:
Pubs id:
pubs:421056
UUID:
uuid:2f83f7d5-8955-4493-b80f-3847b51021d9
Local pid:
pubs:421056
Deposit date:
2013-11-16

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