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The Fasting Hyperglycaemia Study: III. Randomized controlled trial of sulfonylurea therapy in subjects with increased but not diabetic fasting plasma glucose.

Abstract:

Self-referred subjects (N = 227) thought to be at increased risk of developing diabetes who had fasting plasma glucose (FPG) values in the range of 5.5 to 7.7 mmol.L-1 on two consecutive occasions 2 weeks apart were randomized to sulfonylurea therapy (gliclazide, < or = 160 mg.d-1) or to a control group allocated either to double-blind placebo or to no tablets. Subjects were randomly allocated also to reinforced or basic healthy-living advice in a factorial design. A total of 201 subjects ...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
Journal:
Metabolism: clinical and experimental
Volume:
46
Issue:
12 Suppl 1
Pages:
56-60
Publication date:
1997-12-01
Event title:
Conference on Recent Advances in the Management of Type II Diabetes and Impaired Glucose Tolerance
DOI:
EISSN:
1532-8600
ISSN:
0026-0495
Source identifiers:
27049

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