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Journal article

Interleukin 13 inhibits human immunodeficiency virus type 1 production in primary blood-derived human macrophages in vitro.

Abstract:

The mechanisms by which cellular immunity maintains the asymptomatic state after human immunodeficiency virus type 1 (HIV-1) infection are poorly understood. CD4+ T lymphocytes play a complex role in regulating anti-HIV effector pathways, including activation of macrophages, which are themselves implicated in clinical latency and pathogenesis of symptomatic acquired immune deficiency syndrome. We have found that a newly identified T helper type 2 lymphokine, interleukin 13 (IL-13), inhibits H...

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Publication status:
Published

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Publisher copy:
10.1084/jem.178.2.743

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Journal:
The Journal of experimental medicine
Volume:
178
Issue:
2
Pages:
743-747
Publication date:
1993-08-05
DOI:
EISSN:
1540-9538
ISSN:
0022-1007
URN:
uuid:2f04e2e6-5b2e-4d55-9635-27916685f25e
Source identifiers:
21502
Local pid:
pubs:21502

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