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Journal article

Genetic variants of MICB and PLCE1 and associations with non-severe dengue

Abstract:

BACKGROUND: A recent genome-wide association study (GWAS) identified susceptibility loci for dengue shock syndrome (DSS) at MICB rs3132468 and PLCE1 rs3740360. The aim of this study was to define the extent to which MICB (rs3132468) and PLCE1 (rs3740360) were associated with less severe clinical phenotypes of pediatric and adult dengue. METHODS: 3961 laboratory-confirmed dengue cases and 5968 controls were genotyped at MICB rs3132468 and PLCE1 rs3740360. Per-allele odds ratios (OR) with 95% c...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0059067

Authors


Publisher:
Public Library of Science
Journal:
PloS one More from this journal
Volume:
8
Issue:
3
Pages:
e59067
Publication date:
2013-03-11
Acceptance date:
2013-02-11
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Pmid:
23536857
Language:
English
Keywords:
Pubs id:
pubs:390826
UUID:
uuid:2ef0b539-3ae5-4281-ad59-fe8731680b2e
Local pid:
pubs:390826
Source identifiers:
390826
Deposit date:
2017-04-26

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