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The lognormal lung: A new approach to quantifying lung inhomogeneity in COPD

Abstract:

Early diagnosis and disease phenotyping in COPD are currently limited by the use of spirometry, which may remain normal despite significant small-airways disease and which may not fully capture a patient’s underlying pathophysiology. In this study we explored the use of a new non-invasive technique that assesses gas-exchange inhomogeneity in patients with COPD of varying disease severity (according to GOLD Stage), compared with age-matched healthy controls. The technique, which combines hi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fphys.2022.1032126

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Oxford college:
Worcester College
Role:
Author
ORCID:
0000-0003-3206-9793
More by this author
Institution:
University of Oxford
Role:
Author
More by this author
Institution:
University of Oxford
Role:
Author
More by this author
Institution:
University of Oxford
Role:
Author
More by this author
Institution:
University of Oxford
Role:
Author
Publisher:
Frontiers Media
Journal:
Frontiers in Physiology More from this journal
Volume:
13
Article number:
1032126
Publication date:
2022-10-31
Acceptance date:
2022-10-11
DOI:
EISSN:
1664-042X
Language:
English
Keywords:
Pubs id:
1301513
Local pid:
pubs:1301513
Deposit date:
2022-11-11

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