Journal article
Prophylactic acetaminophen or ibuprofen result in equivalent acute mountain sickness incidence at high altitude: a prospective randomized trial
- Abstract:
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Objective Recent trials have demonstrated the usefulness of ibuprofen in the prevention of acute mountain sickness (AMS), yet the proposed anti-inflammatory mechanism remains unconfirmed. Acetaminophen and ibuprofen were tested for AMS prevention. We hypothesized that a greater clinical effect would be seen from ibuprofen due to its anti-inflammatory effects compared with acetaminophen’s mechanism of possible symptom reduction by predominantly mediating nociception in the bra... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted Manuscript
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- Files:
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(pdf, 371.2KB)
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- Publisher copy:
- 10.1016/j.wem.2016.12.011
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Authors
Funding
Wellcome Trust
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Wilderness and Environmental Medicine Journal website
- Volume:
- 28
- Issue:
- 2
- Pages:
- 72-78
- Publication date:
- 2017-05-04
- Acceptance date:
- 2016-12-30
- DOI:
- ISSN:
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1080-6032
- Pubs id:
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pubs:695938
- URN:
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uri:2ee21c6a-5057-4443-a80a-a2bbf4a6fd42
- UUID:
-
uuid:2ee21c6a-5057-4443-a80a-a2bbf4a6fd42
- Local pid:
- pubs:695938
- Paper number:
- 2
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright holder:
- Elsevier Ltd
- Copyright date:
- 2017
- Notes:
-
Copyright © 2017 Elsevier Ltd. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.wem.2016.12.011
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