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The ParMRC system: molecular mechanisms of plasmid segregation by actin-like filaments.

Abstract:

The ParMRC plasmid partitioning apparatus is one of the best characterized systems for bacterial DNA segregation. Bundles of actin-like filaments are used to push plasmids to opposite poles of the cell, whereupon they are stably inherited on cell division. This plasmid-encoded system comprises just three components: an actin-like protein, ParM, a DNA-binding adaptor protein, ParR, and a centromere-like region, parC. The properties and interactions of these components have been finely tuned to...

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Publisher copy:
10.1038/nrmicro2425

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Gayathri, P More by this author
Journal:
Nature reviews. Microbiology
Volume:
8
Issue:
10
Pages:
683-692
Publication date:
2010-10-05
DOI:
EISSN:
1740-1534
ISSN:
1740-1526
URN:
uuid:2ed3e0e8-f511-4173-b604-a64b42a775a6
Source identifiers:
432089
Local pid:
pubs:432089

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