Journal article
Subpopulations and stability in microbial communities
- Abstract:
- In microbial communities, each species often has multiple, distinct phenotypes, but studies of ecological stability have largely ignored this subpopulation structure. Here, we show that such implicit averaging over phenotypes leads to incorrect linear stability results. We then analyze the effect of phenotypic switching in detail in an asymptotic limit and partly overturn classical stability paradigms: Abundant phenotypic variation is linearly destabilizing but, surprisingly, a rare phenotype such as bacterial persisters has a stabilizing effect. Finally, we extend these results by showing how phenotypic variation modifies the stability of the system to large perturbations such as antibiotic treatments.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 733.9KB, Terms of use)
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- Publisher copy:
- 10.1103/physrevresearch.2.022036
Authors
- Publisher:
- American Physical Society
- Journal:
- Physical Review Research More from this journal
- Volume:
- 2
- Issue:
- 2
- Article number:
- 22036
- Publication date:
- 2020-05-12
- Acceptance date:
- 2020-04-16
- DOI:
- EISSN:
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2643-1564
- Language:
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English
- Keywords:
- Pubs id:
-
1108767
- Local pid:
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pubs:1108767
- Deposit date:
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2020-06-05
- ARK identifier:
Terms of use
- Copyright date:
- 2020
- Rights statement:
- Published by the American Physical Society under the terms of the Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI.
- Licence:
- CC Attribution (CC BY)
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