Journal article

Kinetic and thermodynamic azides from alpha-triflates of gamma-lactones: Intermediates for the incorporation of polyhydroxylated D- and L-alpha-aminoacids into combinatorial libraries

Abstract:: Displacement of α-triflates of 2,3,4-all cis-substituted γ-lactones by sodium azide in DMF gives kinetically an azide with inversion of configuration at the C-2 of the lactone; under the reaction conditions, the initially formed azide epimerises to the apparently more crowded and thermodynamically stable all cis-azide, giving intermediates which should readily allow the incorporation of polyhydroxylated amino acids into combinatorial libraries.

Publication status:: Published

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APA Style

Krulle, T., Davis, B., Ardron, H., Long, D., Hindle, N., Smith, C., Brown, D., Lane, A., Watkin, D., Marquess, D., & Fleet, G. (1996). Kinetic and thermodynamic azides from alpha-triflates of gamma-lactones: Intermediates for the incorporation of polyhydroxylated D- and L-alpha-aminoacids into combinatorial libraries. CHEMICAL COMMUNICATIONS, 11, 1271–1272.

MLA Style

Krulle, T., et al. “Kinetic and Thermodynamic Azides from Alpha-Triflates of Gamma-Lactones: Intermediates for the Incorporation of Polyhydroxylated D- and L-Alpha-Aminoacids into Combinatorial Libraries.” CHEMICAL COMMUNICATIONS, no. 11, 1996, pp. 1271–72.

Chicago Style

Krulle, T, B Davis, H Ardron, D Long, N Hindle, C Smith, D Brown, et al. 1996. “Kinetic and Thermodynamic Azides from Alpha-Triflates of Gamma-Lactones: Intermediates for the Incorporation of Polyhydroxylated D- and L-Alpha-Aminoacids into Combinatorial Libraries.” CHEMICAL COMMUNICATIONS, no. 11: 1271–72.
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Publisher copy:: 10.1039/cc9960001271

Authors

+ Krulle, T More by this author

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+ Davis, B More by this author

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+ Ardron, H More by this author

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+ Long, D More by this author

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+ Hindle, N More by this author

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Journal:: CHEMICAL COMMUNICATIONS More from this journal
Issue:: 11
Pages:: 1271-1272
Publication date:: 1996-06-07
DOI:: 10.1039/cc9960001271
EISSN:: 1364-548X
ISSN:: 1359-7345

Language:: English
Pubs id:: pubs:45237
UUID:: uuid:2e9c5ec2-cb13-42fe-acca-aa5e53549d02
Local pid:: pubs:45237
Source identifiers:: 45237
Deposit date:: 2012-12-19

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Copyright date:: 1996

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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