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Journal article

Multiple endocrine neoplasia type 1 (MEN1).

Abstract:

Multiple Endocrine Neoplasia type 1 (MEN1) is an autosomal-dominant disorder characterised by the occurrence of tumours of the parathyroids, pancreas and anterior pituitary. The MEN1 gene, consists of 10 exons that encode a 610-amino acid protein referred to as Menin. Menin is predominantly a nuclear protein that has roles in transcriptional regulation, genome stability, cell division and proliferation. Germ-line mutations usually result in MEN1 or occasionally in an allelic variant referred ...

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Publication status:
Published

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Publisher copy:
10.1016/j.beem.2010.07.003

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Journal:
Best practice and research. Clinical endocrinology and metabolism
Volume:
24
Issue:
3
Pages:
355-370
Publication date:
2010-06-05
DOI:
EISSN:
1878-1594
ISSN:
1521-690X
URN:
uuid:2e63f88a-ae38-4ad2-aa06-b32e76eefdcf
Source identifiers:
73300
Local pid:
pubs:73300

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