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Journal article

Survival and invasion dynamics in cell populations: an analytical framework for threshold behaviour in nonlinear age-structured models

Abstract:

Cell populations invade through a combination of proliferation and motility. Proliferation depends on the internal timing of cell division: how long cells take to complete the cell cycle. This timing varies substantially within (and across) cell types, creating age structure where cells at different times since their last division have different propensities to divide. Classical mathematical models of cell spreading treat division as memoryless and predict exponential cell-cycle-time distribu...

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Publication status:
Accepted
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Role:
Author


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Funder identifier:
https://ror.org/01cmst727
Grant:
MP-SIP-00001828




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