- Abstract:
-
Several lines of evidence link glucose-6-phosphate dehydrogenase (G6PD) deficiency to protection from severe malaria. Early reports suggested most G6PD deficiency in sub-Saharan Africa was because of the 202A/376G G6PD A-allele, and recent association studies of G6PD deficiency have employed genotyping as a convenient way to determine enzyme status. However, further work has suggested that other G6PD deficiency alleles are relatively common in some regions of West Africa. To investigate the c...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Publisher copy:
- 10.1038/ejhg.2009.8
-
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- Publisher:
- Macmillan Publishers Ltd. Publisher's website
- Journal:
- European Journal of Human Genetics Journal website
- Volume:
- 17
- Issue:
- 8
- Pages:
- 1080-1085
- Publication date:
- 2009-08-05
- DOI:
- EISSN:
-
1476-5438
- ISSN:
-
1018-4813
- URN:
-
uuid:2deef271-4eee-4d89-9420-0d726f03573b
- Local pid:
- ora:4333
- Language:
- English
- Keywords:
- Subjects:
- Copyright holder:
- Macmillan Publisher Limited
- Copyright date:
- 2009
- Notes:
- The full-text of this article is not currently available in ORA, but you may be able to access the article via the publisher copy link on this record page. Citation: Clark, T. G. et al. (2009). 'Allelic heterogeneity of G6PD deficiency in West Africa and severe malaria susceptibility', European Journal of Human Genetics 17(8), 1080-1085. [Available at http://www.nature.com/ejhg/journal/v17/n8/full/ejhg20098a.html].
Journal article
Allelic heterogeneity of G6PD deficiency in West Africa and severe malaria susceptibility
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