Parasitological Confirmation and Analysis of Leishmania Diversity in Asymptomatic and Subclinical Infection following Resolution of Cutaneous Leishmaniasis

Journal article

Background The contribution of individuals with subclinical infection to the transmission and endemicity of cutaneous leishmaniasis (CL) is unknown. Immunological evidence of exposure to Leishmania in residents of endemic areas has been the basis for defining the human population with asymptomatic infection. However, parasitological confirmation of subclinical infection is lacking. Methods We investigated the presence and viability of Leishmania in blood and non-invasive mucosal tissue s...

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Authors: Rosales-Chilama, M; Gongora, RE; Valderrama, L; Jojoa, J; Alexander, N

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Public Library of Science
• Journal: PLoS Neglected Tropical Diseases
• Volume: 9
• Issue: 12
• Pages: e0004273-e0004273
• Publication date: 2015-12-11
• DOI: 10.1371/journal.pntd.0004273
• EISSN: 1935-2735
• ISSN: 1935-2727
• Language: English
• Keywords: Biology; Amastigote; Virology; Subclinical infection; Pathology; Leishmaniasis; Parasite hosting; Dermatology; Asymptomatic; Leishmania; Medicine; Immunology; Cutaneous leishmaniasis