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Is anti-viral defence the evolutionary origin of mRNA turnover? (Comment on DOI 10.1002/bies.201600100).

Abstract:
"Is anti-viral defence the evolutionary origin of mRNA turnover?": Comment by J Rehwinkel on "Exaptive origins of regulated mRNA decay in eukaryotes" Hamid and Makeyev (2016; 10.1002/bies.201600100).
In this issue of BioEssays, Hamid and Makeyev explore an interesting new idea regarding the evolutionary origins of regulated mRNA turnover pathways ... This hypothesis – that molecular mechanisms nowadays primarily involved in regulated mRNA decay have their origin in anti-viral defence – provides interesting new perspectives on host-pathogen co-evolution and on molecular recognition of RNA.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/bies.201600140

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM - Investigative Medicine Division
Role:
Author


Publisher:
Wiley
Journal:
Bioessays More from this journal
Volume:
38
Issue:
9
Pages:
817
Publication date:
2016-08-01
Acceptance date:
2016-07-19
DOI:
EISSN:
1521-1878
ISSN:
0265-9247


Language:
English
Keywords:
Pubs id:
pubs:638746
UUID:
uuid:2d1dbcd5-9053-4b37-8315-92ba25a54800
Local pid:
pubs:638746
Source identifiers:
638746
Deposit date:
2016-08-25

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