Extrapolation beyond the end of trials to estimate long term survival and cost effectiveness

Journal article

### Key messages > This paper explains the importance of extrapolating beyond the end of trials to estimate the long term benefits associated with new treatments, why this is done, and the limitations of various approaches. Policy makers worldwide use economic evaluation to inform decisions when.

Authors: Latimer, NR; Adler, AI

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: BMJ Publishing Group
• Journal: BMJ Medicine
• Volume: 1
• Issue: 1
• Pages: e000094-e000094
• Publication date: 2022-03-22
• DOI: 10.1136/bmjmed-2021-000094
• EISSN: 2754-0413
• ISSN: 2754-0413
• Language: English
• Keywords: Cost–benefit analysis; Key (lock); Political science; Mathematics; Business; Computer security; Extrapolation; Statistics; Actuarial science; Term (time); Operations research; Computer science; Engineering; Econometrics; Economics; Risk analysis (engineering)