Journal article
ST2 and IL-33 in pregnancy and pre-eclampsia.
- Abstract:
-
Normal pregnancy is associated with a mild systemic inflammatory response and an immune bias towards type 2 cytokine production, whereas pre-eclampsia is characterized by a more intense inflammatory response, associated with endothelial dysfunction and a type 1 cytokine dominance. Interleukin (IL)-33 is a newly described member of the IL-1 family, which binds its receptor ST2L to induce type 2 cytokines. A soluble variant of ST2 (sST2) acts as a decoy receptor to regulate the activity of IL-3...
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- Publication status:
- Published
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- Publisher copy:
- 10.1371/journal.pone.0024463
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Authors
Bibliographic Details
- Journal:
- PloS one
- Volume:
- 6
- Issue:
- 9
- Pages:
- e24463
- Publication date:
- 2011-01-01
- DOI:
- EISSN:
-
1932-6203
- ISSN:
-
1932-6203
- Source identifiers:
-
248275
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:248275
- UUID:
-
uuid:2d001e08-03bf-48fe-acdf-c572a9fb3931
- Local pid:
- pubs:248275
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2011
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