Diabetes mellitus, glycated haemoglobin and C-peptide levels in relation to pancreatic cancer risk: a study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.

Journal article

AIMS/HYPOTHESIS: There has been long-standing debate about whether diabetes is a causal risk factor for pancreatic cancer or a consequence of tumour development. Prospective epidemiological studies have shown variable relationships between pancreatic cancer risk and blood markers of glucose and insulin metabolism, overall and as a function of lag times between marker measurements (blood donation) and date of tumour diagnosis. METHODS: Pre-diagnostic levels of HbA(1c) and C-peptide were measur...

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Authors: Grote, V; Rohrmann, S; Nieters, A; Dossus, L; Tjønneland, A

• Publication status: Published
• Journal: Diabetologia
• Volume: 54
• Issue: 12
• Pages: 3037-3046
• Publication date: 2011-12-01
• DOI: 10.1007/s00125-011-2316-0
• EISSN: 1432-0428
• ISSN: 0012-186X
• Language: English
• Keywords: C-Peptide; Female; Hemoglobin A, Glycosylated; Adult; Middle Aged; Diabetes Mellitus, Type 2; Male; Aged, 80 and over; Europe; Aged; Humans; Pancreatic Neoplasms; Cohort Studies; Risk