- Abstract:
-
Amide Proton Transfer (APT) reports on contrast derived from the exchange of protons between amide groups and water. Commonly, APT contrast is quantified by asymmetry analysis, providing an ensemble contrast of both amide proton concentration and exchange rate. An alternative is to sample the off-resonant spectrum and fit an exchange model, permitting the APT effect to be quantified, correcting automatically for confounding effects of spillover, field inhomogeneity, and magnetization transfer...
Expand abstract - Journal:
- Magnetic Resonance in Medicine
- Volume:
- 70
- Issue:
- 2
- Pages:
- 556-567
- Publication date:
- 2013-08-05
- DOI:
- EISSN:
-
1522-2594
- ISSN:
-
0740-3194
- URN:
-
uuid:2c0f5afc-0420-4257-bd32-5b32872d20c4
- Source identifiers:
-
418877
- Local pid:
- pubs:418877
- Language:
- English
- Keywords:
- Copyright date:
- 2013
Journal article
Quantitative Bayesian model-based analysis of amide proton transfer MRI
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