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Journal article

Triple bypass: complicated paths to HIV escape.

Abstract:

Human immunodeficiency virus (HIV) type 1 is highly efficient at evading immune responses and persisting, ultimately causing fatal immunodeficiency in some patients. Mutation in the epitopes recognized by cytolytic CD8+ T cells (CTLs) is one such escape process. A new study now shows that one HIV-1 escape mutation may also result in impaired dendritic cell (DC) activity, possibly impairing later T cell responses to the same and other epitopes. The new data complete our understanding of the me...

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Publication status:
Published

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Publisher copy:
10.1084/jem.20072371

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
Journal:
The Journal of experimental medicine
Volume:
204
Issue:
12
Pages:
2785-2788
Publication date:
2007-11-05
DOI:
EISSN:
1540-9538
ISSN:
0022-1007
URN:
uuid:2bab89bc-e6cc-4e0f-9ef6-b6a38aba7494
Source identifiers:
34052
Local pid:
pubs:34052

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