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Journal article

Use of major histocompatibility complex class I tetramers to monitor tumor-specific cytotoxic T lymphocyte response in melanoma patients.

Abstract:

There is now considerable evidence that human tumors often express antigens that render them susceptible to lysis by cytotoxic T lymphocytes (CTLs). These findings have raised hope for the development of cancer vaccines to trigger a tumor-specific immune response in cancer patients. To optimize the immunogenicity of cancer vaccines, it is important to improve the monitoring of the immune response. The use of tetrameric soluble major histocompatibility complex (MHC) class I/peptide complexes (...

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Publication status:
Published

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Publisher copy:
10.1007/pl00014056

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine, Biomedical Research Centre
Role:
Author
Journal:
Cancer chemotherapy and pharmacology
Volume:
46 Suppl
Issue:
SUPPL.
Pages:
S83-S85
Publication date:
2000-01-01
DOI:
EISSN:
1432-0843
ISSN:
0344-5704
URN:
uuid:2b614489-579e-4919-95f9-e8e74beaad87
Source identifiers:
31738
Local pid:
pubs:31738

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