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Genetic variation in COL17A1 and the development of bullous pemphigoid.

Abstract:

BACKGROUND: Bullous pemphigoid (BP) is an autoimmune blistering disease of the skin characterized by autoantibody attack on collagen XVII. OBJECTIVES: To characterize the genetic complexity of COL17A1, the gene which encodes for the autoantigen collagen XVII. The data will be used to determine whether there is an association between polymorphisms and haplotypes of COL17A1 and genetic susceptibility to development of BP. METHODS: The genetic complexity in COL17A1 was deduced by screening and ...

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Publication status:
Published

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Authors


Marshall, SE More by this author
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Journal:
Experimental dermatology
Volume:
13
Issue:
3
Pages:
140-147
Publication date:
2004-03-05
DOI:
EISSN:
1600-0625
ISSN:
0906-6705
URN:
uuid:2b557a9e-e18f-419a-ba46-0cc272733d17
Source identifiers:
11693
Local pid:
pubs:11693

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