- Abstract:
- Opiate peptides are known to elevate circulating GH in man, and data in other animals suggest that acetylcholine may be involved. We have administered the long-acting met-enkephalin analogue DAMME to 6 normal males, and have shown that the resulting elevation in GH is blocked by the specific cholinergic antagonist, pirenzepine. It seems likely that a cholinergic mechanism may interact with opiate-induced changes in GH in man.
- Publication status:
- Published
- Publisher copy:
- 10.1111/j.1365-2265.1983.tb00585.x
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- Journal:
- Clinical endocrinology
- Volume:
- 18
- Issue:
- 4
- Pages:
- 401-405
- Publication date:
- 1983-04-05
- DOI:
- EISSN:
-
1365-2265
- ISSN:
-
0300-0664
- URN:
-
uuid:2b35a9c5-13a5-4ba2-a816-423cc024a51b
- Source identifiers:
-
138662
- Local pid:
- pubs:138662
- Copyright date:
- 1983
Journal article
Opiate peptides control growth hormone through a cholinergic mechanism in man.
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