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Journal article

Light-Patterned Current Generation in a Droplet Bilayer Array

Abstract:
We have created a 4 × 4 droplet bilayer array comprising light-activatable aqueous droplet bio-pixels. Aqueous droplets containing bacteriorhodopsin (bR), a light-driven proton pump, were arranged on a common hydrogel surface in lipid-containing oil. A separate lipid bilayer formed at the interface between each droplet and the hydrogel; each bilayer then incorporated bR. Electrodes in each droplet simultaneously measured the light-driven proton-pumping activities of each bio-pixel. The 4 × 4 array derived by this bottom-up synthetic biology approach can detect grey-scale images and patterns of light moving across the device, which are transduced as electrical current generated in each bio-pixel. We propose that synthetic biological light-activatable arrays, produced with soft materials, might be interfaced with living tissues to stimulate neuronal pathways.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/srep46585

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Chemistry Research Laboratory
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Chemistry Research Laboratory
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Chemistry Research Laboratory
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Chemistry Research Laboratory
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Chemistry Research Laboratory
Role:
Author


Publisher:
Springer Nature
Journal:
Scientific reports More from this journal
Volume:
7
Pages:
46585
Publication date:
2017-04-18
Acceptance date:
2017-03-17
DOI:
ISSN:
2045-2322
Pmid:
28417964


Language:
English
Keywords:
Pubs id:
pubs:690869
UUID:
uuid:2b24a0ab-a2d9-4da0-aea8-248a63da1db3
Local pid:
pubs:690869
Source identifiers:
690869
Deposit date:
2017-10-19

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