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Both the H13 gene product and 4F2 antigen are involved in the induction of system y⁺ cationic amino-acid transport following activation of human peripheral blood mononuclear cells (PBM)

Abstract:

Prior transfection with antisense oligonucleotides to the H13 and 4F2 hc genes, singly or in combination, was found to inhibit phytohaemagglutinin-induced activation of cationic amino-acid transport system y+ in human peripheral blood mononuclear cells (mostly circulating lymphocytes). These effects on system y+ function or expression mean that 4F2 hc cannot only be the molecular basis of system y+L.

Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/0005-2736(96)00125-3

Authors


Sarah Chen More by this author
David Meredith More by this author
More by this author
Institution:
University of Oxford
Department:
Medical Sciences Division - Physiology,Anatomy and Genetics,Department of
Publisher:
Elsevier Science B.V.
Journal:
Biochimica et Biophysica Acta (BBA) - Biomembranes Journal website
Volume:
1284
Issue:
1
Pages:
1–3
Publication date:
1996-10-05
DOI:
ISSN:
0005-2736
URN:
uuid:2af993c1-48e7-4180-b8fd-0d4c0d85b612
Local pid:
ora:8102

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