Journal article

Neonatal diabetes - The role of KCNJ11 (Kir6.2)

Abstract:: ATP-sensitive potassium (KATP) channels are inhibited by intracellular ATP and activated by MgADP. As a consequence, they couple the metabolic state of the cell to its electrical activity. In pancreatic β-cells KATP channels regulate glucose-dependent insulin secretion and are the target for sulphonylurea drugs clinically employed in the treatment of type 2 diabetes. This review discusses recent advances in our understanding of the role of KATP channels in permanent neonatal diabetes mellitus. Copyright © 2007 S. Karger AG.

Publication status:: Published

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Share
Cite

Cite this record

APA Style

Tammaro, P. (2007). Neonatal diabetes - The role of KCNJ11 (Kir6.2). CONGENITAL ENDOCRINOPATHIES, 11, 70–82.

MLA Style

Tammaro, P. “Neonatal Diabetes - The Role of KCNJ11 (Kir6.2).” CONGENITAL ENDOCRINOPATHIES, vol. 11, 2007, pp. 70–82.

Chicago Style

Tammaro, P. 2007. “Neonatal Diabetes - The Role of KCNJ11 (Kir6.2).” CONGENITAL ENDOCRINOPATHIES 11: 70–82.
Print

Access Document

Publisher copy:: 10.1159/000111059

Authors

+ Tammaro, P More by this author

Institution:: University of Oxford
Division:: MSD
Department:: Pharmacology
Role:: Author

Journal:: CONGENITAL ENDOCRINOPATHIES More from this journal
Volume:: 11
Pages:: 70-82
Publication date:: 2007-01-01
DOI:: 10.1159/000111059
EISSN:: 1662-2979
ISSN:: 1421-7082

Language:: English
Pubs id:: pubs:381350
UUID:: uuid:2aaf01e4-6e95-46ff-8f5c-430d37a2b44d
Local pid:: pubs:381350
Source identifiers:: 381350
Deposit date:: 2013-11-16
ARK identifier:: ark:/29072/ora_2aaf01e46e9546ff8f5c430d37a2b44d

Terms of use

Copyright date:: 2007

Licence:: Terms and Conditions of Use for Oxford University Research Archive

Views and Downloads

About views and downloads

If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP