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Immune correlates of protection for dengue: State of the art and research agenda

Abstract:

Dengue viruses (DENV1-4) are mosquito-borne flaviviruses estimated to cause up to ∼400 million infections and ∼100 million dengue cases each year. Factors that contribute to protection from and risk of dengue and severe dengue disease have been studied extensively but are still not fully understood. Results from Phase 3 vaccine efficacy trials have recently become available for one vaccine candidate, now licensed for use in several countries, and more Phase 2 and 3 studies of additional vacci...

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Publication status:
Published
Peer review status:
Peer reviewed

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Authors


Katzelnick, LC More by this author
Participants In The Summit On Dengue Immune Correlates Of Protection More by this author

Contributors

Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Role:
Contributor
World Health Organization More from this funder
National Institutes of Health More from this funder
Publisher:
Elsevier Publisher's website
Volume:
35
Issue:
36
Pages:
4659-4669
Publication date:
2017-07-28
Acceptance date:
2017-07-13
DOI:
EISSN:
1873-2518
ISSN:
0264-410X
Pubs id:
pubs:820695
URN:
uri:2a7f58bd-fe89-4ee6-a14a-d32bca50936e
UUID:
uuid:2a7f58bd-fe89-4ee6-a14a-d32bca50936e
Local pid:
pubs:820695

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