Journal article

Safe drugs with high potential to block malaria transmission revealed by a spleen-mimetic screening

Abstract:: Authors propose their splenic mimetic filtration method, microsphiltration, and utilise this approach in a drug-screen, to identify compounds that induce a stiffening effect on Plasmodium falciparum-infected erythrocytes. They proceed to assess safety and tolerability of one identified compound in a phase I clinical trial

Publication status:: Published

Peer review status:: Peer reviewed

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Share
Cite

Cite this record

APA Style

Carucci, M., Duez, J., Tarning, J., García-Barbazán, I., Fricot-Monsinjon, A., Sissoko, A., Dumas, L., Gamallo, P., Beher, B., Amireault, P., Dussiot, M., Dao, M., Hull, M. V., McNamara, C. W., Roussel, C., Ndour, P. A., Sanz, L. M., Gamo, F. J., & Buffet, P. (2023). Safe drugs with high potential to block malaria transmission revealed by a spleen-mimetic screening. Nature Communications, 14(1), 1951–1951.

MLA Style

Carucci, M, et al. “Safe Drugs with High Potential to Block Malaria Transmission Revealed by a Spleen-Mimetic Screening.” Nature Communications, vol. 14, no. 1, 2023, pp. 1951–51.

Chicago Style

Carucci, M, J Duez, J Tarning, et al. 2023. “Safe Drugs with High Potential to Block Malaria Transmission Revealed by a Spleen-Mimetic Screening.” Nature Communications 14 (1): 1951–51.
Print

Access Document

Files:: Carucci_et_al_2023_Safe_drugs_with.pdf

(Preview, Version of record, pdf, 3.1MB, Terms of use)

Publisher copy:: 10.1038/s41467-023-37359-2

Publication website:: https://repisalud.isciii.es/bitstream/20.500.12105/16532/1/SafeDrugsHighPotential_2023.pdf

Authors

+ Carucci, M More by this author

Role:: Author

+ Duez, J More by this author

Role:: Author
ORCID:: 0000-0002-5416-5084

+ Tarning, J More by this author

Institution:: University of Oxford
Role:: Author
ORCID:: 0000-0003-4566-4030

+ García-Barbazán, I More by this author

Role:: Author
ORCID:: 0000-0003-4372-9646

+ Fricot-Monsinjon, A More by this author

Role:: Author
ORCID:: 0000-0002-8648-2770

More authors...

+ Bill and Melinda Gates Foundation More from this funder

Funder identifier:: 10.13039/100000865
Grant:: OPP1123683

+ U.S. Department of Health & Human Services | National Institutes of Health More from this funder

Funder identifier:: 10.13039/100000002
Grant:: R01HL154150

Publisher:: Nature Research
Journal:: Nature Communications More from this journal
Volume:: 14
Issue:: 1
Pages:: 1951-1951
Article number:: 1951
Publication date:: 2023-04-07
DOI:: 10.1038/s41467-023-37359-2
EISSN:: 2041-1723
ISSN:: 2041-1723

Language:: English
Keywords:: Plasmodium falciparum

Medicine

In vitro

Immunology

Biochemistry

Pharmacology

In vivo

Pharmacokinetics

Virology

Biotechnology

Transmission (telecommunications)

Malaria

Drug

Spleen

Clearance

Biology
Pubs id:: 1337979
Local pid:: pubs:1337979
Source identifiers:: W4362698521
Deposit date:: 2026-05-07
ARK identifier:: ark:/29072/ora_29adf300843244c6ae68d707b43e2206

Terms of use

Copyright date:: 2023

Licence:: CC Attribution (CC BY)

Views and Downloads

About views and downloads

If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP